Non-Invasive vagus nerve stimulation (gammaCore)

A device for treatment of cluster headache and migraine

Non-Invasive vagus nerve stimulation (gammaCore)

gammaCore™ is a simple-to-use, handheld medical device that enables patients to self-administer discrete doses of non-invasive vagus nerve stimulation (nVNS) therapy. gammaCore is a CE-mark approved, non-medicinal treatment for adults who suffer from primary headache conditions such as migraine and cluster headache.

  • nVNS therapy has been shown to be a safe and effective treatment option for the management of cluster headache, in clinical trials
  • gammaCore works by sending a mild electrical stimulation through the skin to activate the vagus nerve from outside your body
  • Stimulation of the vagus nerve works in several ways to relieve cluster headache and migraine pain

On 22 October 2018, the National Institute for Health and Care Excellence (NICE) published a Medtech Innovation Briefing on gammaCore (nVNS) for use in the treatment of cluster headache in adults.

gammaCore Sapphire

gammaCore Sapphire™ is a rechargeable and reloadable version of the product intended for multi-year use. It is activated on a regular (typically every 3 months) basis through the input of a unique, prescription-only authorization code, delivered via a radio-frequency identification, or RFID, card.

The improved design features of gammaCore Sapphire include:

  • A sleeker, smaller handheld device that is easy for patients to grip
  • Smoother stimulation surfaces for easy placement over the vagus nerve
  • Intensity buttons positioned on the side of the device to facilitate therapy adjustments
  • A larger, brighter display to communicate status information, even in the dark

gammaCore is only available in the UK following authorisation by a specialist healthcare professional (typically a consultant neurologist and/or their headache team). Please contact your local specialist or GP for a referral.

Accessing treatment

Further reading