16th December 2019

Neuroscientist awarded The Migraine Trust PhD studentship for project that seeks to fill critical gap in understanding of migraine

Hannah Creeney will be studying the neurophysiological role of amylin in migraine

Hannah Creeney

We are delighted to announce that neuroscientist Hannah Creeney has been awarded our latest PhD studentship. Hannah who is from London will be studying the neurophysiological role of amylin in migraine, a project that is being led by Dr Jan Hoffmann and Dr Philip Holland at the Institute of Psychiatry, Psychology and Neuroscience, King’s College London.

Amylin is a neuropeptide that is known to have similar mechanisms to calcitonin gene-related peptide (CGRP), a neuropeptide that is released during migraine attacks and can increase the activation of the nerves that relay headache and facial pain signals to the brain. Amylin and CGRP bind to each other’s receptor and this research will examine if amylin’s actions on these receptors are relevant for migraine. The research aims to determine if an increased understanding of amylin could lead to a new treatment for migraine.

Help those who are living with migraine

The project has a personal element for Hannah, who has a BSc in Biochemistry from Imperial College London and a MSc in Neuroscience from King’s College London, as she has several family and friends who get migraine. Knowing how difficult it is to live with she hopes that her research will help improve the lives of the millions of people worldwide who are affected by migraine.

Explaining why she is undertaking the PhD, Hannah said:

“I have a strong interest in translational neuroscience research and decided to focus my efforts on understanding the mechanisms which underlie brain disorders. As someone with several family and friends who get migraine, I am motivated to learn more about the disorder and to contribute to research which could improve treatment outcomes and have an impact on the lives of millions of patients worldwide.”

Congratulating Hannah on being awarded the studentship, Gus Baldwin, Chief Executive of The Migraine Trust, said:

“Hannah’s research is aiming to fill a critical gap in our understanding of the mechanisms behind migraine. The potential for developing new and ground-breaking treatments as a result of this research is huge and very exciting. It could transform the lives of those who live with this painful and debilitating brain disease.

“The fact that Hannah has several people close to her who get migraine means that she personally knows the life-change possibilities of this research.

“I also want to pay tribute to our amazing supporters for their donations, and The Headley Trust for their substantial contribution, which has enabled us to fund this exciting and important research. They are playing a key role in furthering the understanding of why we get migraine so that hopefully a cure can one day be found.”